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中文人类
POLR2B - RNA Polymerase II Subunit B
Alias:
RPB2
POL2RB
hRPB140
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这个基因编码RNA聚合酶II（Pol II）的第二大亚基，这是一个依赖于DNA的RNA聚合酶，能够催化将DNA转录成mRNA、snRNA和microRNA的前体。这个亚基和最大的亚基在Pol II的中心裂隙的对立面形成。删除这个亚基的flap loop区域会导致转录延长速率降低。可变剪接导致多个转录变异体。[由RefSeq，2014年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
POLR2B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
