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中文人类
POLR2A - RNA Polymerase II Subunit A
Alias:
RPB1
RPO2
POLR2
POLRA
RPBh1
RPOL2
NEDHIB
RpIILS
hsRPB1
hRPB220
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这个基因编码真核生物中负责合成信使RNA的RNA聚合酶II的最大亚基。这个基因的产物包含一个羧基末端结构域，由七肽重复序列组成，这对于聚合酶活性是必不可少的。这些重复序列包含在活跃转录中磷酸化的丝氨酸和苏氨酸残基。此外，这个亚基与其他几个聚合酶亚基结合，形成聚合酶的DNA结合结构域，一个将DNA模板转录成RNA的沟槽。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
POLR2A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
