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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Grik2 - glutamate ionotropic receptor kainate type subunit 2
Alias:
GluK2
GluR6
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括PDZ结构域结合活性;酶结合活性;以及海人酸选择性谷氨酸受体活性。参与多种过程,包括谷氨酸能突触传递的负调控;神经元凋亡过程的正调控;以及JNK级联的调控。位于树突质膜;胞质;和终端小突。是质膜的整合成分。是离子型谷氨酸受体复合物的一部分。该基因的人类同源物与亨廷顿病和常染色体隐性非综合征性智力残疾有关。与人类GRIK2(谷氨酸离子型受体海人酸型亚型2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:54257
ENSEMBL:ENSRNOG00000000368
UNIPROT:P42260
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
54257
1
16
697737 bp
102.47
9
11
Grik2 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
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