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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
App - amyloid beta precursor protein
Alias:
Abeta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活生长因子受体结合活性和肽酶激活物活性。参与几个过程,包括细胞对金属离子的反应;对其他生物体的防御反应;以及MAPK级联的正向调节。位于几个细胞成分中,包括星形胶质细胞突起;轴突;和粗糙内质网。用于研究阿尔茨海默病。阿尔茨海默病的生物标志物;糖尿病性脑病;高血压;缺铁性贫血;和中脑动脉梗死。这个基因的人类同源物涉及与APP相关的脑淀粉样血管病;阿尔茨海默病;阿尔茨海默病1;认知障碍;和视觉癫痫。与人类APP(淀粉样前体蛋白)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:54226
ENSEMBL:ENSRNOG00000006997
UNIPROT:P08592
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
54226
6
18
216811 bp
86.70
47
26
App Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
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Interactions
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Acting
Regulation
Detail
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Target
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Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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