Log In|Sign Up
中文人类
TREM2 - Triggering Receptor Expressed On Myeloid Cells 2
Alias:
PLOSL2
TREM-2
Trem2a
Trem2b
Trem2c
Favorite
这个基因编码一个膜蛋白，与TYRO蛋白酪氨酸激酶结合蛋白形成受体信号复合体。编码的蛋白质在免疫应答中发挥作用，可能通过触发组成性炎症细胞因子的产生参与慢性炎症。这个基因的缺陷是导致多囊性脂质膜性骨发育不良伴硬化性脑白质营养不良（PLOSL）的原因之一。可变剪接产生多个转录变异体，编码不同的异构体。[RefSeq, Nov 2012提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TREM2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
