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中文小鼠
Ppm1d - protein phosphatase 1D magnesium-dependent, delta isoform
Alias:
Wip1
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预测能够激活有丝分裂原激活的蛋白激酶结合活性和蛋白质丝氨酸/苏氨酸磷酸酶活性。参与DNA甲基化和异染色质组装。在DNA损伤响应、p53类介导的信号传导、有丝分裂细胞周期的G2/M过渡以及响应细菌的过程中发挥上游或内部作用。预测位于核仁核浆中。预测在细胞质和细胞核中活跃。在包括肾上腺、泌尿系统、肠道、血淋巴样系统腺体和表皮系统在内的几个结构中表达。这个基因的人类同源物与乳腺癌有关。与人类的PPM1D(蛋白磷酸酶,Mg2+/Mn2+依赖性1D)正交。[由基因组资源联盟,2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ppm1d Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
