人类

PRKAG3 - Protein Kinase AMP-activated Non-catalytic Subunit Gamma 3

Alias:
AMPKG3
SMGMQTL
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是AMP激活的蛋白激酶(AMPK)的调节亚基。AMPK是一个由alpha催化亚基、非催化性beta亚基和gamma亚基组成的三聚体。AMPK是一种重要的能量感应酶,监测细胞能量状态。响应细胞代谢压力,AMPK被激活,从而磷酸化并失活乙酰辅酶A羧化酶(ACC)和β-羟基β-甲基戊酸辅酶A还原酶(HMGCR),这些是参与调节脂肪酸和胆固醇新生合成的关键酶。这个亚基是AMPK的gamma调节亚基之一。它主要表达在骨骼肌中。对猪对应物的研究提示,这个亚基可能在骨骼肌能量代谢调节中起关键作用。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
14
9496 bp
54.26
42
1
7
10

PRKAG3 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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