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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Porcn - porcupine O-acyltransferase
Alias:
Ppn
Mg61
porc
Mporc
mMg61
DXHXS7465e
2410004O13Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活Wnt蛋白结合活性和棕榈酸转移酶活性。参与Wnt信号通路、蛋白棕榈酸脂代谢和突触后膜神经递质受体水平的调节。在正则Wnt信号通路和糖蛋白代谢过程中发挥上游或内部作用。位于内质网和谷氨酸能突触中。是内质网膜的组成部分。是AMPA谷氨酸受体复合物的组成部分。在几个结构中表达,包括前内脏内胚层、眼睛、生殖泌尿系统、神经系统和原条。用于研究焦点皮肤发育不良。该基因的人类同源物与焦点皮肤发育不良有关。与人类PORCN(刺猬O-酰基转移酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:53627
ENSEMBL:ENSMUSG00000031169
UNIPROT:Q9JJJ7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
53627
10
15
12710 bp
52.51
9
9
Porcn Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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