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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PLXNA2 - Plexin A2
Alias:
OCT
PLXN2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个plexin-A家族的semaphorin协同受体成员。semaphorins是一大类可分泌或膜结合的蛋白质,在神经系统发育过程中对轴突路径的识别具有排斥作用。一部分semaphorins被plexin-A/神经磷脂跨膜受体复合物识别,触发细胞信号转导级联,导致轴突排斥。这个plexin-A家族成员被认为可以传递来自semaphorin-3A和-3C的信号。[由RefSeq,2008年7月提供]
Related ID:
NCBI:5362
ENSEMBL:ENSG00000076356
HGNC:9100
UNIPROT:O75051
OMIM:601054
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5362
3
32
222143 bp
211.10
425
--
7
8
PLXNA2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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