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中文人类
MBD3 - Methyl-CpG Binding Domain Protein 3
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DNA甲基化是真核生物基因组的主要修饰方式，在哺乳动物发育中起着关键作用。这个基因属于核蛋白家族，以其存在甲基-CpG结合结构域（MBD）为特征。编码的蛋白质是NuRD的多亚基复合体的亚单位，该复合体含有核小体重塑和组蛋白脱乙酰酶活性。与其他家族成员不同，编码的蛋白质不能结合甲基化的DNA。该蛋白质介导转移蛋白2与核心组蛋白脱乙酰酶复合体的关联。可变剪接导致这个基因的多个转录变异体。[RefSeq，2013年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MBD3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
