Nono - non-POU-domain-containing, octamer binding protein

Enables chromatin binding activity. Involved in negative regulation of transcription, DNA-templated and regulation of circadian rhythm. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including brain; central nervous system ganglion; gut; sensory organ; and testis. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 34. Orthologous to human NONO (non-POU domain containing octamer binding). [provided by Alliance of Genome Resources, Apr 2022]