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中文人类
PLCG2 - Phospholipase C Gamma 2
Alias:
FCAS3
APLAID
PLC-IV
PLC-gamma-2
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这个基因编码的蛋白质是一种跨膜信号酶，它使用钙作为辅因子，催化1-磷酸磷脂酰-1D-肌醇4,5-二磷酸酯转化为1D-肌醇1,4,5-三磷酸酯（IP3）和二酰基甘油（DAG）。IP3和DAG是第二信使分子，对于从生长因子受体和免疫系统受体传递信号穿过细胞膜非常重要。这个基因的突变与自身炎症、抗体缺陷和免疫调节综合症以及家族性冷自身炎症综合症3有关。[RefSeq提供，2014年3月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLCG2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
