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中文人类
BCL11A - BCL11 Transcription Factor A
Alias:
EVI9
CTIP1
DILOS
ZNF856
HBFQTL5
SMARCM1
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这个基因编码一个C2H2型锌指蛋白，与小鼠Bcl11a/Evi9蛋白相似。相应的小鼠基因是髓细胞白血病中逆转录病毒整合的常见位点，可能作为白血病疾病基因发挥作用，部分是通过与BCL6相互作用。在造血细胞分化过程中，这个基因被下调。它可能参与淋巴瘤的发病机制，因为与B细胞恶性肿瘤相关的易位也会改变其表达。已经发现这个基因有多个转录变异体，编码几个不同的异构体。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BCL11A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
