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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Dlg3 - discs large MAGUK scaffold protein 3
Alias:
Dlgh3
SAP102
mKIAA1232
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使泛素蛋白连接酶具有结合活性。参与调节突触后膜神经递质受体的水平。在平面极性的建立和上皮细胞顶/基底极性的建立或维持中起到上游或内部作用。位于几个细胞组件中,包括双细胞紧密连接;谷氨酸能突触;和质膜。AMPA谷氨酸受体复合物的一部分。在中枢神经系统和视网膜中表达。用于研究非综合征性X连锁智力障碍。这个基因的人类同源物与非综合征性X连锁智力障碍90有关。与人类DLG3(discs large MAGUK支架蛋白3)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:53310
ENSEMBL:ENSMUSG00000000881
UNIPROT:P70175
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
53310
11
21
50817 bp
93.48
6
8
Dlg3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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