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中文人类
PLA2G4A - Phospholipase A2 Group IVA
Alias:
GURDP
cPLA2
PLA2G4
cPLA2-alpha
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这个基因编码一个细胞质磷脂酶A2族IV成员。该酶催化膜磷脂的水解，释放花生四烯酸，随后代谢成前列腺素和白细胞三烯。前列腺素和白细胞三烯是调节血液动力学、炎症反应和其他细胞内途径的基于脂质的细胞激素。水解反应还产生溶血磷脂，使其转化为血小板激活因子。该酶由增加的细胞内Ca(2+)水平和磷酸化激活，导致其从细胞质和细胞核转移到核周膜囊泡。可选剪接产生多种转录变异体。[由RefSeq，2015年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLA2G4A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
