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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PLA2G2A - Phospholipase A2 Group IIA
Alias:
MOM1
PLA2
PLA2B
PLA2L
PLA2S
PLAS1
sPLA2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是磷脂酶A2家族(PLA2)的成员。PLA2s构成了一种在序列、功能、定位和二价阳离子需求方面具有多样性的酶家族。这个基因产物属于II组,其中包含磷脂酶A2的分泌形式,这是一种外周酶,分子量低,催化需要钙离子。它催化磷脂酰甘油的sn-2脂肪酸酰酯键的水解,释放游离脂肪酸和溶磷脂,被认为参与调节生物膜中的磷脂代谢。这个基因发现了几种具有不同5'UTR的剪接转录变体。[由RefSeq提供,2009年9月]
Related ID:
NCBI:5320
ENSEMBL:ENSG00000188257
HGNC:9031
UNIPROT:P14555
OMIM:172411
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5320
8
5
5004 bp
16.08
7
1
--
23
PLA2G2A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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