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中文人类
PLA2G1B - Phospholipase A2 Group IB
Alias:
PLA2
PLA2A
PPLA2
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这个基因编码一种分泌型的磷脂酶A2（PLA2）类酶成员，由胰腺腺泡细胞产生。该酶是钙依赖性酶，催化膜甘油磷脂在sn-2位的水解，释放花生四烯酸（AA）和溶血磷脂酰胆碱。AA随后被下游代谢酶转化为几种生物活性亲脂化合物（类二十烷酸），包括前列腺素（PGs）和白细胞三烯（LTs）。该酶可能涉及几个生理过程，包括细胞收缩、细胞增殖和病理反应。[RefSeq，2013年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLA2G1B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
