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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PKM - Pyruvate Kinase M1/2
Alias:
PK3
TCB
p58
OIP3
PKM2
CTHBP
THBP1
HEL-S-30
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种参与糖酵解的蛋白质。编码的蛋白质是一种丙酮酸激酶,催化磷酸烯醇丙酮酸上的磷酸基团转移到ADP上,产生ATP和丙酮酸。这个蛋白质已被证明与甲状腺激素相互作用,可能调节甲状腺激素诱导的细胞代谢效应。这个蛋白质已被发现与Opa蛋白结合,Opa蛋白是涉及淋球菌粘附和侵入人细胞的一种细菌外膜蛋白,这表明这个蛋白质在细菌致病中的作用。已经报道了几种可变剪接的转录变异体,编码几种不同的异构体。[由RefSeq提供,2011年5月]
Related ID:
NCBI:5315
ENSEMBL:ENSG00000067225
HGNC:9021
UNIPROT:P14618
OMIM:179050
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5315
17
11
32563 bp
57.94
16
--
16
52
PKM Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Related Mouse Models
Type
Name
MGI
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Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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