Log In|Sign Up
中文人类
PIN1 - Peptidylprolyl Cis/trans Isomerase, NIMA-interacting 1
Alias:
DOD
UBL5
Favorite
肽基-脯氨酰顺/反异构酶（PPIases）催化肽基-脯氨酰肽键的顺/反异构化。这个基因编码一种特定的PPIase，它可以与磷酸化的ser/thr-pro基序结合，以催化调节其底物的磷酸化后构象。这个PPIase催化的构象调节对参与细胞生长调节、基因毒性和其他应激反应、免疫反应、多能性诱导和维护、生殖细胞发育、神经元分化和生存的关键蛋白具有深远影响。这个酶在阿尔茨海默病和许多癌症的病理发生中也扮演关键角色。这个基因发现有多种可变剪接转录变异体。[RefSeq，2011年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PIN1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
