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中文人类
PIK3R1 - Phosphoinositide-3-kinase Regulatory Subunit 1
Alias:
p85
AGM7
GRB1
IMD36
p85alpha
p85-ALPHA
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磷脂酰肌醇3-激酶在3'端位置对磷脂酰肌醇的肌醇环进行磷酸化。该酶包含一个110kD的催化亚基和85、55或50kD的调节亚基。该基因编码85kD的调节亚基。磷脂酰肌醇3-激酶在胰岛素的代谢作用中扮演重要角色，该基因的突变与胰岛素抵抗有关。该基因的可变剪接导致四个转录变异体，编码不同的异构体。[由RefSeq，2011年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PIK3R1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
