人类

SERPINB8 - Serpin Family B Member 8

Alias:
PI8
CAP2
PI-8
PSS5
C18orf53
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是ov-serpin家族丝氨酸蛋白酶抑制剂的一员。编码的蛋白质由血小板产生,可以与furin(一种参与血小板功能的丝氨酸蛋白酶)结合并抑制其功能。此外,该蛋白质已被发现能增强皮肤中细胞间粘附的力学稳定性,而该基因的缺陷与常染色体隐性遗传型剥脱性鱼鳞病有关[RefSeq,2017年1月提供]。

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
7
49699 bp
42.77
56
3
3
7

SERPINB8 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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