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中文人类
PFKFB2 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Alias:
PFK-2/FBPase-2
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这个基因编码的蛋白质涉及2,6-二磷酸果糖的合成和降解，2,6-二磷酸果糖是一种在真核生物中调节糖酵解的调控分子。编码的蛋白质具有6-磷酸果糖-2-激酶活性，催化2,6-二磷酸果糖的合成，以及果糖-2,6-双磷酸酶活性，催化2,6-二磷酸果糖的降解。这个蛋白质调节心脏中2,6-二磷酸果糖的水平，而由不同基因编码的相关的酶则调节肝脏和肌肉中2,6-二磷酸果糖的水平。这个酶作为同源二聚体发挥作用。已经发现这个基因有两个转录变异体，编码两种不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PFKFB2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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References Literature
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