人类

PFKFB1 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Alias:
F6PK
HL2K
PFRX
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个双功能6-磷酸果糖-2-激酶:果糖-2,6-二磷酸酶酶家族的成员。这个酶形成一种催化合成和降解果糖-2,6-二磷酸酸使用独立催化结构域的同二聚体。果糖-2,6-二磷酸酸是糖酵解途径的激活剂和糖异生途径的抑制剂。因此,通过这个酶的活性调节果糖-2,6-二磷酸酸的水平被认为可以调节葡萄糖的稳态。已经发现了这个基因的多种可变剪接转录变异体。[由RefSeq,2012年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
14
65829 bp
54.68
14
--
4
7

PFKFB1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top