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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PFDN5 - Prefoldin Subunit 5
Alias:
MM1
MM-1
PFD5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码prefoldin alpha亚基家族的一员。编码的蛋白质是prefoldin的六个亚基之一,prefoldin是一种结合并稳定新生多肽的分子伴侣复合物,从而使其正确折叠。该复合物由两个alpha和四个beta亚基组成,形成具有六个突出螺旋的双β筒组装。编码的蛋白质也可能抑制原癌基因c-Myc的转录活性。已经描述了编码不同异构体的可变剪接转录变异体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:5204
ENSEMBL:ENSG00000123349
HGNC:8869
UNIPROT:Q99471
OMIM:604899
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5204
2
6
3909 bp
17.33
--
--
4
12
PFDN5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Mutations
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Transcripts & Proteins
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Transcript
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CDS(bp)
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Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
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Status
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References Literature
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