Rgs14 - regulator of G-protein signaling 14

Enables GTPase activating protein binding activity and GTPase activator activity. Involved in several processes, including learning or memory; negative regulation of signal transduction; and regulation of synaptic plasticity. Acts upstream of or within mitotic cell cycle. Located in several cellular components, including glutamatergic synapse; microtubule cytoskeleton; and postsynaptic density. Is expressed in decidua; embryo; hippocampus CA2; neural ectoderm; and placenta. Human ortholog(s) of this gene implicated in nephrolithiasis. Orthologous to human RGS14 (regulator of G protein signaling 14). [provided by Alliance of Genome Resources, Apr 2022]