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中文人类
WWOX - WW Domain Containing Oxidoreductase
Alias:
FOR
WOX1
DEE28
EIEE28
FRA16D
SCAR12
HHCMA56
PRO0128
SDR41C1
D16S432E
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这个基因编码短链脱氢酶/还原酶（SDR）蛋白家族的成员。这个基因跨越FRA16D常见染色体脆性位点，并似乎具有肿瘤抑制基因的功能。编码的蛋白质的表达能够诱导细胞凋亡，而该基因的缺陷与多种类型的癌症相关。这个基因的破坏也与常染色体隐性脊髓小脑性共济失调12相关。小鼠中类似基因的破坏导致类固醇生成受损，此外提示该蛋白质具有代谢功能。可变剪接导致多个转录变异体。[由RefSeq，2014年5月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
WWOX Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
