Log In|Sign Up
中文人类
PDZK1 - PDZ Domain Containing 1
Alias:
CAP70
CLAMP
PDZD1
NHERF3
NHERF-3
Favorite
这个基因编码一个包含PDZ结构域的支架蛋白。PDZ结构域分子与靶蛋白质结合并调节其亚细胞定位。编码的蛋白质调节细胞表面蛋白质的定位，并通过调节HDL受体，清道夫受体B1型在胆固醇代谢中扮演关键角色。这个基因的单核苷酸多态性可能与代谢综合症有关，这个基因的过度表达可能在多发性骨髓瘤的药物抗性中发挥作用。这个基因的假基因位于染色体1的长臂上。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[由RefSeq，2011年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDZK1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
