人类

ACSL5 - Acyl-CoA Synthetase Long Chain Family Member 5

Alias:
ACS2
ACS5
FACL5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是长链脂肪酸辅酶A连接酶家族的一个同工酶。尽管在底物特异性、亚细胞定位和组织分布上存在差异,但这个家族的所有同工酶都将自由的长链脂肪酸转化为脂肪酸酰辅酶A酯,从而在脂质生物合成和脂肪酸降解中起到关键作用。这个同工酶在子宫和脾脏中高度表达,而在正常大脑中的含量很少,但在恶性神经胶质瘤中水平显著增加。这个基因在调节脂肪酸诱导的神经胶质瘤细胞生长中发挥作用。已经发现这个基因有三个转录变异体,编码两种不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
21
54261 bp
75.99
27
1
10
14

ACSL5 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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