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中文人类
PDGFRA - Platelet Derived Growth Factor Receptor Alpha
Alias:
CD140A
PDGFR2
PDGFR-2
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这个基因编码一个细胞表面酪氨酸激酶受体，用于血小板来源的生长因子家族的成员。这些生长因子是间充质来源的细胞的促细胞分裂剂。与受体单体结合的生长因子的身份决定了功能性受体是同二聚体还是异二聚体，由血小板来源的生长因子受体α和β多肽组成。研究表明，这个基因在器官发育、伤口愈合和肿瘤进展中发挥作用。这个基因的突变与特发性高嗜酸性综合症、体细胞和家族性胃肠道间质瘤以及多种其他癌症有关。[RefSeq，2012年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDGFRA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
