人类

GSKIP - GSK3B Interacting Protein

Alias:
HSPC210
C14orf129
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种蛋白质,作为GSK3-beta在Wnt信号通路中的负调控因子。编码的蛋白质可能通过调节GSK3-beta、beta-catenin和细胞周期蛋白D1之间的功能相互作用,在视黄酸信号通路中发挥作用。该蛋白质在其C端含有与GSK3-beta相互作用的结构域(GID),与Axin的GID相似。该蛋白质还包含一个进化保守的RII结合结构域,有助于与蛋白激酶A和GSK3-beta结合,使其成为A-激酶锚定蛋白。已经观察到了这个基因的可变剪接转录变异体。[RefSeq,2012年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
4
23765 bp
15.65
12
--
3
9

GSKIP Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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