人类

PDE8A - Phosphodiesterase 8A

Alias:
HsT19550
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于环核苷酸磷酸二酯酶(PDE)家族,以及PDE8亚家族。这个PDE水解第二信使,cAMP,cAMP是一种调节剂,并介导许多细胞对细胞外信号的响应。因此,通过调节cAMP的细胞浓度,这个蛋白质在许多重要的生理过程中扮演关键角色。已经发现这个基因有不同的剪接转录变异体,它们编码不同的异构体。[由RefSeq,2011年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
11
22
158676 bp
93.30
37
--
6
13

PDE8A Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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