人类

PDE4B - Phosphodiesterase 4B

Alias:
DPDE4
PDEIVB
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是IV型,环AMP(cAMP)特异性的环核苷酸磷酸二酯酶(PDE)家族的一员。编码的蛋白质调节细胞内环核苷酸浓度,从而在信号传导中发挥作用。这个蛋白质的活性改变与精神分裂症和双相情感障碍有关。可变剪接和替代启动子的使用导致多个转录变异体,编码不同的异构体。[由RefSeq,2014年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
12
17
582070 bp
83.34
15
--
7
16

PDE4B Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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