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中文人类
PDE1C - Phosphodiesterase 1C
Alias:
Hcam3
DFNA74
hCam-3
cam-PDE 1C
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这个基因编码一种属于3'5'-环核苷酸磷酸二酯酶家族的酶。这个家族的成员催化环核苷酸，即环腺苷酸和环鸟苷酸的水解，转化为相应的核苷5'-单磷酸。这个基因编码的酶调节血管平滑肌细胞的增殖和迁移，以及内膜增生。这个酶还通过调节生长因子受体的稳定性，如PDGF-受体-beta，在病理血管重塑中发挥作用。[RefSeq，2016年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDE1C Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
