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中文人类
PDE1A - Phosphodiesterase 1A
Alias:
HCAM1
HCAM-1
HSPDE1A
CAM-PDE 1A
CAM-PDE-1A
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环核苷酸磷酸二酯酶（PDEs）通过将cAMP和/或cGMP水解为其相应的核苷5'-单磷酸，在信号传导中扮演角色，从而调节细胞内环核苷酸浓度。PDE1家族的成员，如PDE1A，是Ca(2+)/钙调素（参见CALM1；MIM 114180）依赖的PDEs（CaM-PDEs），在Ca(2+)存在下被钙调素激活（Michibata等人，2001年[PubMed 11342109]；Fidock等人，2002年[PubMed 11747989]）。[由OMIM于2009年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDE1A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
