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中文人类
PDCD1 - Programmed Cell Death 1
Alias:
PD1
PD-1
CD279
SLEB2
hPD-1
hPD-l
hSLE1
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程序性细胞死亡蛋白1（PDCD1）是一种在激活的T细胞中表达的免疫抑制受体；它参与调节T细胞功能，包括效应CD8+ T细胞的功能。此外，这种蛋白还能促进CD4+ T细胞分化为调节性T细胞。PDCD1在许多类型的肿瘤中表达，包括黑素瘤，并已证明在抗肿瘤免疫中发挥作用。此外，这种蛋白已被证明涉及对抗自身免疫的保护作用，然而，它也可能有助于抑制有效的抗肿瘤和抗微生物免疫。[由RefSeq，2020年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDCD1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
