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中文人类
TLR8 - Toll Like Receptor 8
Alias:
CD288
IMD98
hTLR8
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这个基因编码的蛋白质是Toll样受体（TLR）家族的一员，在病原体识别和先天免疫激活中起基本作用。TLRs从果蝇到人类高度保守，并在结构和功能上相似。它们识别感染剂上表达的病原体相关分子模式（PAMPs），并调节产生有效免疫发展所需的细胞因子。各种TLR表现出不同的表达模式。这个基因主要在肺和外周血白细胞中表达，并与另一个家庭成员TLR7在染色体X上紧密相邻。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TLR8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
