人类

MARCHF2 - Membrane Associated Ring-CH-type Finger 2

Alias:
MARCH2
RNF172
HSPC240
MARCH-II
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
MARCH2是膜结合E3泛素连接酶MARCH家族的成员(EC 6.3.2.19)。MARCH酶将泛素添加到底物蛋白质的靶定赖氨酸上,从而信号传递其在内质网膜区室之间的囊泡运输。MARCH2降低几种糖蛋白的表面积累,并似乎调节早期内质网到高尔基网(TGN)的运输(Bartee等人,2004[PubMed 14722266];Nakamura等人,2005[PubMed 15689499])。[由OMIM在2010年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
5
25713 bp
27.00
10
--
5
12

MARCHF2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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