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中文人类
HERC5 - HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 5
Alias:
CEB1
CEBP1
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这个基因是泛素连接酶HERC家族的成员，编码一个具有HECT结构域和五个RCC1重复序列的蛋白质。前炎症细胞因子在内皮细胞中上调这个基因的表达。这个蛋白质定位在细胞质和核周区域，作为干扰素诱导的E3蛋白连接酶，调节蛋白质靶标的ISGylation。这个蛋白质还作为抗病毒免疫应答的调节物。这个基因位于染色体4上的HERC家族基因簇中。[RefSeq，2021年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HERC5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
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