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中文人类
IRAK4 - Interleukin 1 Receptor Associated Kinase 4
Alias:
IPD1
IMD67
REN64
IRAK-4
NY-REN-64
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这个基因编码一种激酶，可以在Toll样受体（TLR）和T细胞受体（TCR）信号通路中激活NF-kappa B。该蛋白对大多数天然免疫反应是必不可少的。这个基因的突变导致IRAK4缺陷和反复发生的侵袭性肺炎球菌疾病。已经发现这个基因有多种转录变异体，编码不同的异构体。[RefSeq，2011年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IRAK4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
