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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GLRX2 - Glutaredoxin 2
Alias:
GRX2
CGI-133
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是谷胱甘肽还原酶家族的成员,该家族的蛋白质维持细胞硫醇稳态。这些蛋白质是硫醇-二硫键氧化还原酶,它们使用谷胱甘肽结合位点和活性位点中的一个或两个活性半胱氨酸。这个基因经历可变剪接产生多个等位基因,其中一个是普遍表达的,并定位到线粒体,其中它在线粒体氧化还原稳态中发挥作用,并对保护和恢复氧化应激至关重要。其他等位基因,其表达模式更为严格,显示胞质和核定位,并被认为在细胞分化和转化中发挥作用,可能在肿瘤进展中发挥作用。[由RefSeq提供,2011年8月]
Related ID:
NCBI:51022
ENSEMBL:ENSG00000023572
HGNC:16065
UNIPROT:Q9NS18
OMIM:606820
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
51022
3
4
9650 bp
18.05
8
--
5
13
GLRX2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Related Mouse Models
Type
Name
MGI
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Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
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IF
No Data Found!
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