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中文人类
ASCC1 - Activating Signal Cointegrator 1 Complex Subunit 1
Alias:
p50
CGI-18
SMABF2
ASC1p50
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这个基因编码激活信号整合子1（ASC-1）复合物的亚基。ASC-1复合物是一种转录共激活子，在由多种转录因子包括激活蛋白1（AP-1）、核因子kappa-B（NF-kB）和血清响应因子（SRF）进行的基因转激活中发挥着重要作用。编码的蛋白质含有N-末端KH型RNA结合基序，这是ASC-1复合物通过AP-1转激活所必需的。这个基因的突变与巴雷特食管和食管腺癌有关。已经观察到了这个基因的替代剪接转录本，它们编码多种异构体。[RefSeq，2011年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ASCC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
