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中文人类
PDE11A - Phosphodiesterase 11A
Alias:
PPNAD2
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3',5'-环核苷酸cAMP和cGMP作为第二信使参与多种信号转导途径。3',5'-环核苷酸磷酸二酯酶(PDEs)催化cAMP和cGMP水解为相应的5'-单磷酸酯，从而下调cAMP和cGMP信号传导。此基因编码PDE蛋白超家族的一员。此基因的突变是库欣病和肾上腺皮质增生症的原因。已发现此基因有多个编码不同异型的转录变异体。[由RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PDE11A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
