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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Keap1 - kelch-like ECH-associated protein 1
Alias:
INRF2
mKIAA0132
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有无序结构域特异性的结合活性,并具有相同的蛋白质结合活性。参与细胞蛋白质代谢过程;细胞对氧化应激的反应;以及自噬的调节。在几个过程的上游或内部发挥作用,包括细胞对白介素-4的反应;子宫内胚胎发育;以及表皮细胞分化的调节。位于肌动蛋白丝;内质网;和包涵体中。是Cul3-RING泛素连接酶复合物的一部分。在眼和肢芽基质中表达。该基因的人类同源物与胆囊癌有关。与人类KEAP1(kelch样ECH关联蛋白1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:50868
ENSEMBL:ENSMUSG00000003308
UNIPROT:Q9Z2X8
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
50868
4
5
9603 bp
69.55
15
32
Keap1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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