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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
KCNK4 - Potassium Two Pore Domain Channel Subfamily K Member 4
Alias:
FHEIG
TRAAK
K2p4.1
TRAAK1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码TWIK相关的一成员,这个成员是花生四烯酸刺激的两孔钾通道亚家族。编码的蛋白质能够形成同源二聚体,并作为外向整流通道发挥作用。这个通道受到多不饱和脂肪酸、温度和脂质膜机械变形的影响。这个蛋白质主要在神经组织中表达,可能参与调节背根节神经元的有害输入阈值。交替剪接导致多个转录变异体。自然发生的直通转录本存在于这个基因和下游的睾丸表达40(TEX40)基因之间,如GeneID: 106780802所示。[由RefSeq,2015年11月提供]
Related ID:
NCBI:50801
ENSEMBL:ENSG00000182450
HGNC:6279
UNIPROT:Q9NYG8
OMIM:605720
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
50801
2
7
8730 bp
42.70
289
2
4
11
KCNK4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
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Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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