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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Postn - periostin, osteoblast specific factor
Alias:
PN
PLF
Osf2
OSF-2
A630052E07Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种分泌性的细胞外基质蛋白,在包括心肌梗死后的伤口愈合和心室重塑的组织发育和再生中发挥作用。编码的蛋白质与整合素结合,支持上皮细胞的粘附和迁移。这种蛋白质在癌症干细胞维持和转移中发挥作用。缺乏这个基因的小鼠表现出心脏瓣膜疾病以及骨骼和牙齿缺陷。可变剪接导致多个转录变异体,编码不同的异构体。[由RefSeq,2015年9月提供]
Related ID:
NCBI:50706
ENSEMBL:ENSMUSG00000027750
UNIPROT:Q62009
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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50706
6
21
31775 bp
93.14
14
10
Postn Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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