小鼠

Elane - elastase, neutrophil expressed

Alias:
NE
Ela2
F430011M15Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码丝氨酸蛋白酶类的一员,该家族成员可以水解广泛的蛋白质底物,包括弹性蛋白。这个基因被中性粒细胞表达,其中编码的酶储存在嗜中性粒颗粒中。在中性粒细胞激活后,活性酶释放到细胞外环境中。缺乏编码的蛋白质的小鼠对腹腔感染革兰阴性细菌后的脓毒症和死亡易感性增加。这个基因位于染色体10上与一个相关的蛋白酶基因相邻。[由RefSeq,2016年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
5
1905 bp
28.65
7
4

Elane Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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