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中文人类
PAM - Peptidylglycine Alpha-amidating Monooxygenase
Alias:
PAL
PHM
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这个基因编码一个多功能蛋白质。编码的前原蛋白质在蛋白水解过程中被加工成成熟的酶。这种酶包括两个具有不同催化活性的结构域，一个肽基甘氨酸α-羟化单加氧酶（PHM）结构域和一个肽基-α-羟基甘氨酸α-酰胺化酶（PAL）结构域。这些催化结构域依次工作，催化神经内分泌肽转化为活性α-酰胺化产物。可变剪接导致多个转录变异体，至少其中一个编码一种经过蛋白水解加工的异构体。[由RefSeq，2016年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PAM Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
