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中文人类
PAK3 - P21 (RAC1) Activated Kinase 3
Alias:
ARA
bPAK
MRX30
MRX47
OPHN3
PAK-3
XLID30
PAK3beta
beta-PAK
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这个基因编码的蛋白质是一种丝氨酸-苏氨酸激酶，并与GTP结合的RAS样(P21)、CDC2和RAC1形成激活复合物。这个蛋白质可能对树突的发展以及树突棘中与突触塑性相关的细胞骨架快速重组是必要的。这个基因的缺陷是导致一种非综合征性X连锁智力障碍的原因。已经发现了编码不同异构体的可变剪接转录变异体。[由RefSeq，2017年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PAK3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
