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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Gja5 - gap junction protein, alpha 5
Alias:
Cx40
Cxni
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种蛋白质,具有连接蛋白结合活性、无序结构域特异性结合活性和间隙连接通道活性。参与多个过程,包括血管直径维持、细胞化学偶联通信和血压调节。位于细胞突起中,是连接蛋白复合物的一部分。用于研究高血压、动脉疾病的生物标志物(多种)、肾小球肾炎、肥胖和输尿管梗阻。这个基因的人类同源基因与房颤、心房停滞1、家族性房颤和法洛四联症有关。与人类的GJA5(间隙连接蛋白α5)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:50563
ENSEMBL:ENSRNOG00000017484
UNIPROT:P28234
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
50563
2
2
19546 bp
40.23
10
5
Gja5 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
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