人类

NOX4 - NADPH Oxidase 4

Alias:
KOX
KOX-1
RENOX
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码NOX家族酶的一员,作为NADPH氧化酶复合体的催化亚基。编码的蛋白质定位在非吞噬性细胞中,作为氧气传感器并催化分子氧还原为各种活性氧物种(ROS)。这种蛋白质产生的ROS与多种生物功能有关,包括信号传导、细胞分化和肿瘤细胞生长。在染色体11的另一个臂上发现了一个假基因。可选的剪接导致多个转录变异体。[由RefSeq,2009年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
18
265205 bp
66.93
29
--
16
21

NOX4 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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