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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
NOX4 - NADPH Oxidase 4
Alias:
KOX
KOX-1
RENOX
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码NOX家族酶的一员,作为NADPH氧化酶复合体的催化亚基。编码的蛋白质定位在非吞噬性细胞中,作为氧气传感器并催化分子氧还原为各种活性氧物种(ROS)。这种蛋白质产生的ROS与多种生物功能有关,包括信号传导、细胞分化和肿瘤细胞生长。在染色体11的另一个臂上发现了一个假基因。可选的剪接导致多个转录变异体。[由RefSeq,2009年1月提供]
Related ID:
NCBI:50507
ENSEMBL:ENSG00000086991
HGNC:7891
UNIPROT:Q9NPH5
OMIM:605261
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
50507
8
18
265205 bp
66.93
29
--
16
21
NOX4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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